Cholesterol and statins The theory that cholesterol ‘blocks arteries’, that it causes heart attacks and strokes is an Cholestérol, mensonges et propagande. : CHOLESTEROL, MENSONGES ET PROPAGANDE, 2EME EDITION ():: Books. Cholestérol mensonges et propagande. 2 likes. Book.
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One of the biggest questions facing clinical cardiology today is the decision on when propaganve treat healthy people with statin drugs. Data from randomized clinical trials show that cholestril treatment may be beneficial for individuals with high risk of developing cardiovascular disease.
However, statins are not without side effects, therefore we have to be sure that the risk of harm does not outweigh the presumed benefits. Statins lower blood cholesterol. They also appear to have a few other effects which may be beneficial for people with established cardiovascular disease. Randomized clinical trials have shown that statins reduce the risk of death and new cardiovascular events among individuals with coronary heart disease.
Not prescribing statins to people who may benefit from such therapy is considered bad medical practice, unless the patient is intolerant to statin treatment. In fact, more than 70 percent of people older lropagande 60 years may become eligible for such treatment. The major criticisms of the guidelines as they pertain to statins are concerns about adverse effects and lack of benefit on total mortality. Today, everybody should know that statins have side effects. Although most are relatively benign, serious life threatening adverse events have been reported.
Such side effects are rare, but they are a cause for concern if millions of healthy people are to be treated with these drugs. Part of the recommendations are based on risk calculation, assuming that when a certain amount of risk is present, the benefit of therapy outweighs the potential harm. However, there are some important questions remaining unanswered such as: How common are side effects from statins in real life, and does the current scientific literature provide reliable data to answer this question?
Interestingly, apart from a slightly increased risk of diabetes and mild elevation of liver enzymes, side effects were not more common among patients receiving statins compared with those on placebo. Researchers at Imperial College looked back at 29 trials involving more than 80, patients taking the cholesterol lowering drugs.
They concluded that the chance propagnde experiencing debilitating symptoms like nausea and fatigue was slightly less among people taking statins than for control groups given a placebo. Now the scientists are calling for drug companies to make it clear on packets that side effects are uncommon so that people are not wrongly dissuaded from treatment.
The Side Effects of Statins
Around seven million people take statins in Britain, a figure that could rise to 12 million under draft NHS guidelines, currently chilestrol for consultation, which will advise the majority of men over 50 and women over 60 to take the drug as a precaution. Health experts have voiced concerns that the cholestroo effects could outweigh the benefits for healthy people.
One of the authors of the paper, Dr. Ben Goldacre has commented on the media reports on his website, Bad Science:. Remarkably, people report typical statin side effects even when they are only receiving placebo: Assessing side effects of statins by using data from randomized clinical trials testing the efficacy of these drugs is problematic in many ways.
Second, methods used to detect and assess side effects are not defined. Fourth, there is selection bias. Patients not eligible for clinical trials are often sicker, have more kidney failure, diabetes and high blood pressure. These individuals may have higher risk of side effects from statins.
Fifth, many trials have placebo run-in periods to test compliance. This may further select highly motivated patents who are less choestrol to report side effects. Let me quote him:.
That is a big piece of work because companies generally refuse to share CSRs…. Liver and muscle problems are the most common side effects of statin therapy. Liver tests are usually monitored and the drug is stopped if there are significant abnormalities. Muscle ache is common. Muscle damage can occur and in rare cases it may become serious.
There appears to be increased risk of diabetes on statin therapy. Some studies have reported changes in memory, attention, or concentration on statins. There are some reports on changes in mood on statins. These include loss of interest in activities and loss of interest in social involvement. Studies have confirmed that peripheral neuropathy tingling and numbness or burning pain may occur with statins.
Sleep problems, sexual function problems, fatigue, dizziness and a sense of detachment are also reported with these drugs. It is of huge importance for clinicians and patients to have access to reliable information on the risk of side effects of statins.
Mensnges the other hand, the risk of side effects from statin therapy appears small. Therefore doctors can also inflict harm to their patients by exaggerating potential side effects which might lead to a patients unwillingness to accept treatment that is of potential benefit. Doctors worrying about the safety of cholesterol-reducing statins are creating a misleading level of uncertainty that could lead to at the loss of lives….
On the other hand, rare side effects may become important when treatment is given to a large proportion of the population. However, a substantial number of people experience side effects. I fear these side effects are more common and sometimes more propagwnde than the propagandd from randomized clinical trials have suggested.
People who have experienced side effects often feel that they are not listened to. Many of these side effects are never reported. If you have any experience from statins, good or bad, no matter whether you are a patient, a medical professional or just a proopagande geek, here might be a good place to tell your story. Two months ago i had an arterial occlusion at age It was easy to notice the side effects of the statin 80 mg.
Cutting the dose to 20 mg.
Switching to Crestor 10 mgs. My choice is now, which of the alternative side effects are more bearable. Or, at what point do I simply stop taking this stuff? Peter Muscle ache is the most commonly experienced side effect of statins. Lowering the dose is sometimes helpful but not always. Changing to another statin drug may sometimes help as well. In my experience, muscle pain is the most common reason why people have to stop taking statins. Thanks for sharing your experience.
Dizziness when leaning over and standing back up. The scariest episode of this occurred in a grocery store. I could see where I was but could no longer tell which direction I was facing. This only lasted a few seconds,but it happened several other times out in the yard. Wanted me to take Crestor next,which I find outrageous.
Alternative Santé – Tout sur le cholestérol – Alternative Santé
It was as if she did not even read my complaint list! Anyone who thinks these things have no side effects and are harmless is out of their blooming mind.
And have not seen the Dr. Please share your story at StatinVictims. We want to mensongfs as many stories as possible in order to gain credence.
Do you think the reduction in Co Q 10 has implications whether the patient has noted side effects or not? In theory CoQ10 might cholsstrol some of the side effects of statins. Some researchers have proposed that taking a coenzyme Q10 supplement might reduce the risk of these side effects.
Memoire Online – Synthèse, transport et excretion du cholestérol dans l’organisme – Aime Mawisa
However, no large studies have confirmed this theory. There are mixed reports on the benefits of CoQ10 in helping statin-associated muscle pain. Mendonges reviews highlight the lack of evidence to support routine CoQ10 supplementation even though there are few safety concerns with such supplementation. I have very limited experience myself with CoQ10 in the context of statin side effects but it seems that more research data is needed to clarify the issue. It was the only way I could continue to take mine.
The aches were so bad I just couldnt cope I need to work. NO side effects at all. Peter — why would your doctor put you on such a high dose of Atorvastatin? What were your lipids like? Are you and Daci aware that some of the statins are derived from mold. Some studies have indicated that higher dose statin therapy is more effective than lower dose therapy in patients with coronary disease.
However, higher dose statins are associated with statistically significantly increased risks of muscle pain and abnormal liver function tests compared to lower mensonhes statins.
I was put on Krestor about 10 years ago, and suffered serious muscle pain. We stopped that, and my doctor put me on Lipidil, which sent propaganxe to the brink of total kidney failure. My doctor is happy with my biannual cholesterol panels.
I was only on a statin for a short time and now I have after two months sever shoulder muscle pain. I have RA mehsonges it was in remission and now Propatande have no Idea what is mensonves on so am going to a Rheumatologist soon. I would rather die than take that drug again! All because of cholesterol numbers. There are some reports of people getting ALS and other debilitation muscle diseases after taking statins.
Why are they not tell the public about this? Secondary analyses of the existing randomized trial data using individual patient data and multivariate adjustment will be needed to appropriately examine proagande incremental benefits of different LDL targets Haywardand future trials will have to determine whether lower dose statin therapy plus other lipid lowering agents may achieve better LDL levels and clinical outcomes than maximal dose statin therapy.